Paper Title

METHOD DEVELOPMENT AND VALIDATION OF ALBUTEROL AND IPTATROPIUM BROMIDE IN TABLET DOSAGE FORM BY USING RP-HPLC

Abstract

An additional suitable expression for a pharmaceutical is active pharmaceutical ingredient (API) / active ingredient to differentiate it from a devised product / drug product is ready by designing a drug sub with inert ingredient (excipient) to prepare a drug product that is appropriate for admin to patients.
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Paper Title

ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF LESINURAD AND ALLOPURINOL IN ITS BULK AND PHARMACEUTICAL DOASGE FORM BY RP-HPLC METHOD

Abstract

HPLC is based on the mechanism of adsorption, partition, ion exchange or size exclusion, depending on the type of stationary phase used. HPLC involves a solid stationary phase, normally packed inside a stainless- steel column, and a liquid mobile phase. Separation of the components of a solution results from difference in the relative distribution ratios of the solutes between the two phases.
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Paper Title

SIMULTANEOUS ESTIMATION PHARMACEUTICAL DOASGE FORM BY RP-HPLC THROUGH SSAY METHOD

Abstract

High performance liquid chromatography is a very sensitive analytical technique most widely used for quantitative and qualitative analysis of pharmaceuticals. HPLC is based on the mechanism of adsorption, partition, ion exchange or size exclusion, depending on the type of stationary phase used. HPLC involves a solid stationary phase, normally packed inside a stainless- steel column, and a liquid mobile phase. Separation of the components of a solution results from difference in the relative distribution ratios of the solutes between the two phases.
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Paper Title

PREPARATION OF ORAL CONTROLLED RELEASE TABLETS OF LACOSAMIDE AND INVITRO EVALUATION

Abstract

The oral controlled release system of many drugs has been known to be an essential part of formulation development in drug delivery systems. It has been the focus of pharmaceutical research for many years due to its various advantages over conventional dosage forms. Administering the drug for release in the blood at a controlled rate, to maintain relatively constant drug levels in plasma over a controlled period of time, can overcome many problems associated with conventional dosage forms. The applicability of these dosage forms is due to reduction in the frequencies of drug dosing, which lead to patient convenience and compliance. In addition, a reduction of wide fluctuations in plasma drug concentration peak can be obtained. As a result, toxicity and poor efficacy can be avoided, especially with drugs of narrow therapeutic indices. Such problems, associated with conventional dosage forms of many drugs, can be overcome by using controlled release drug delivery systems, to deliver the drug for absorption at a controlled rate over an extended period of time. The controlled release dosage form should be tailored so that variations in the components can lead to predictable alterations in the drug release profiles. Various controlled release drug delivery systems have different mechanisms to control the drug release rate, such as the osmotic pump, ion exchange resin and matrix systems which have been widely utilized as controlled release drug delivery approaches. Besides, polymers have often been used in the components of controlled release drug delivery systems. A sustained release profile, without occurring of the dose dumping, and sufficient bioavailability can be achieved when a drug is embedded in some polymeric materials such as gelucires. The presant work focuses on preparing lacosamide controlled release(CR) tablets
KEYWORDS : Lacosamide, CR etc