Paper Title

COMPARATIVE STUDY OF MINERAL PROFILES IN DIOSCOREA SPECIES

Abstract

The research study examines the Dioscorea species, commonly known as yams, within the Dioscoreaceae family, which includes about 600 species found in various tropical regions. These tubers are significant for their carbohydrate content and various bioactive compounds with potential medicinal properties, including diosgenin, which is linked to numerous health benefits. The study emphasizes the need for further pharmacological research to validate the ethnomedicinal uses of Dioscorea species, which are traditionally used to treat a variety of ailments. The research also highlights the importance of mineral analysis in three species: Dioscorea bulbifera, D. esculenta, and D. alata, utilizing atomic absorption spectroscopy for precise mineral content determination. Results indicate varying levels of essential minerals among the species, suggesting their nutritional importance. The conclusion advocates for incorporating these yams into daily diets due to their rich mineral content and potential health benefits, while also calling for conservation efforts due to the decline of these plants in the wild.
KEYWORDS : Nutrient uptake potential

Paper Title

A REVIEW ON ANTI-HEADLICE ACTIVITY OF ANNONA SQUAMOSA SEED EXTRACTS

Abstract

ANNONA SQUMOSA is also known as custard apple and sitaphal. It has known active ingredient that kills Hadlice. Various parts of ANNONA SQUMOSA are use or different purpose, such as the seed extract being applie as a cream, oil, powder to kill Headlice and other parts likes leaves and bark being utilized for treating arrange of element. The present study focused on efficacy and stability of seed extract formulated as a cream.
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Paper Title

FORMULATION AND EVALUATION OF HERBAL FACE PACK

Abstract

The present work involves the formulation and evaluation of a herbal face pack prepared from commonly used natural ingredients. The aim of the study was to develop a safe, skin-friendly, and cost-effective cosmetic preparation using plant materials with known cleansing, soothing, and protective properties. Selected herbal powders were mixed in suitable proportions to obtain a smooth, fine, and stable face pack blend. The prepared formulation was evaluated for its organoleptic characteristics, physicochemical parameters such as pH, moisture content, texture, spread ability, and washability, along with stability and irritation tests. The results showed that the herbal face pack possessed good consistency, acceptable pH, easy washability, and no signs of irritation on application. Overall, the study suggests that the formulated herbal face pack can serve as a natural alternative to chemical-based cosmetic products and may support healthy skin when used regularly.
KEYWORDS : Herbal face pack, Natural formulation, Plant-based ingredients, Physicochemical evaluation, Stability assessment, Skin compatibility, Cosmetic preparation, Anti-inflammatory activity, Moisture control, & Dermatological safety

Paper Title

A REVIEW ON HERBAL ELIXIR FORMULATION ON ASHWAGANGHA (WITHANIA SOMNIFERA)

Abstract

Ashwagandha (Withania somnifera) is a well-known Ayurvedic rasayana herb recognized for its immune-enhancing and adaptogenic properties. This review highlights its key immunomodulatory actions, including improved macrophage activity, balanced cytokine response, and increased natural killer cell function. The formulation of an Ashwagandha-based herbal elixir using a hydroalcoholic base allows efficient extraction of active constituents and offers better absorption than conventional forms. Combining supportive herbs such as Giloy, Tulsi, Amla, Ginger, and Pippali further strengthens antioxidant, antimicrobial, and bioenhancing effects. Overall, an Ashwagandha elixir represents a promising natural approach for boosting immunity, with future clinical validation needed to confirm long-term safety and efficacy.
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Paper Title

REVIEW ARTICLE ON : FORMULATION, EVALUATION AND COMPARISON OF HERBAL SHAMPOO WITH MARKETED SHAMPOO

Abstract

The study aimed to formulate a pure herbal shampoo and to evaluate and compare its Physicochemical properties with marketed synthetic and herbal shampoos. The Herbal shampoo was formulated by adding the extract of bhringraj, amla, lemon, neem, Tulsi, henna, Hibiscus, and bramhi. A small amount of Methyl paraben was added as a preservative, and pH was adjusted with citric acid. Several tests were performed to determine the physiochemical properties of both prepared and marketed shampoo, such as visual inspection, pH, wetting time, % of solid content, foam value and stability, surface tension, detergency, and dirt dispersion. The formulated shampoo showed good cleansing and detergency, low surface tension, small bubble size, and good foam stability after 5 minutes. The prepared shampoo and commercial shampoo also showed comparable results for % solid content. The result indicated that the formulated shampoo has excellent conditioning performance, on par with commercially available shampoo.
KEYWORDS : Herbal shampoo, cosmetic, Antibacterial and Antifungal.

Paper Title

REVIEW ARTICLE ON : POLY-HERBAL HAND SANITIZER

Abstract

The growing demand for natural and safe alternatives to chemical-based hand sanitizers has led to the exploration of herbal formulations with antimicrobial properties. This study focuses on the formulation and evaluation of a polyherbal hand sanitizer using extracts of lemon (Citrus limon), papaya (Carica papaya), and aloe vera (Aloe barbadense miller). The selected herbs are known for their potent antimicrobial, antioxidant, and skin-soothing properties. The hand sanitizer was prepared using herbal extracts, glycerin, Carbopol, and natural fragrances to create a stable and skin-friendly gel. The formulation was evaluated for physicochemical properties, including pH, viscosity, spread ability, and stability, along with antimicrobial efficacy against common pathogens such as Escherichia coli and Staphylococcus aureus. Results indicated that the polyherbal hand sanitizer exhibited excellent antibacterial activity, maintained a skin-friendly pH, demonstrated good spread ability, and remained stable over a three-month observation period. The study concludes that the developed polyherbal hand sanitizer is an effective, natural, and safe alternative to conventional alcohol-based products.
KEYWORDS : Polyherbal hand sanitizer, Herbal formulation, antimicrobial properties, Antibacterial activity.

Paper Title

REVIEW ARTICLE ON : ADVANCE HERBAL TECHNOLOGY

Abstract

Recently peoples are getting attracted towards herbal medicines due to many advantages. Herbal formulations have reached extensive acceptability as therapeutic agents for several diseases. Although, most of these applications are unorthodox, it is however a known fact that over 80% of the world population depends on herbal medicines and product for healthy living. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers’ and manufacturers’ disappointment and in some instances fatal consequences. The development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analyses of marker/bioactive compounds and other major constituents, is a major challenge to scientists. Standardization is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assurance program for production and manufacturing of herbal drugs. In present review article various convectional methods as well as newer advances are described. Recent advancements includes DNA fingerprinting, metabolomics technique, differintial pulse polarography, chemometric, X-ray diffraction etc. are observed. Capillary electrophoresis and chromatographic techniques contributions towards standardization of herbal drugs is also reporte
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Paper Title

REVIEW ON ANTIFUNGAL HAIR OINTMENT

Abstract

An antibacterial hair ointment is a topical semi-solid formulation designed to address and prevent bacterial infections of the scalp and hair. It provides a targeted solution for common issues like folliculitis and other scalp conditions caused by microbial growth. This ointment combines a base of petroleum jelly or natural waxes with active antibacterial agents, which can be synthetic, like mupirocin, or natural, derived from plants.
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Paper Title

REVIEW ARTICLE ON : FORMULATION AND EVALUATION OF POLY- HERBAL ANTI-AGING CREAM.

Abstract

The present study aimed to formulate and evaluate a polyherbal anti-aging cream incorporating extracts of traditionally recognized botanicals with antioxidant and skin-rejuvenating properties. Herbal ingredients such as Aloe vera, Curcuma longa, Emblica officinalis, Azadirachta indica, and Camellia sinensis were selected based on their reported anti-oxidative, anti-inflammatory, and collagen-protective activities. A stable oil-in-water emulsion base was developed, and the polyherbal extracts were incorporated using optimized concentrations to ensure desirable texture, spreadability, and skin compatibility. The formulated cream was subjected to physicochemical evaluation, including pH determination, viscosity analysis, homogeneity, spreadability, and accelerated stability studies. Antioxidant potential was assessed using DPPH radical scavenging assay, while in-vitro anti-aging activity was evaluated through collagenase and elastase inhibition tests. The polyherbal cream demonstrated favorable physicochemical characteristics, high antioxidant capacity, and significant inhibitory activity against collagenase and elastase, indicating its potential to reduce oxidative stress and delay the appearance of aging signs. Overall, the results suggest that the formulated polyherbal cream is a promising natural alternative for anti-aging skincare applications.
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Paper Title

REVIEW ON FORMULATION AND EVALUATION OF COLD CREAM

Abstract

Cold cream has been one of the oldest known semisolid emulsions for cosmetic and pharmaceutical applications. Traditionally, it is recognized as a cleansing and moisturizing formulation intended to calm and protect the skin from dryness and environmental factors. Cold cream is primarily a water-in-oil (W/O) emulsion, composed of natural or synthetic oils, waxes, and water with emulsifiers like borax. The term “cold” refers to the perceived cooling experience upon application due to evaporating water. Cold cream formulations have adapted from simple Galenic preparations to modern multifunctional formulations with humectants, herbal extracts, and bioactive components. This review will describe the history, formulation design, mechanism, evaluation parameters, and recent developments with cold cream technologies. In addition, the relevance of cold cream in the skin and cosmetic industries will be discussed with emphasis on its thriving economy used in both skincare and as a base for pharmaceuticals.
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Paper Title

A STUDY ON THE IMPACT OF MULTICOMPONENT THERAPY ON DEPRESSIVE SYMPTOMS AMONG HIGH SCHOOL STUDENTS IN SELECTED SCHOOLS AT KOLLAM, KERALA

Abstract

High school kids are particularly susceptible to teenage depression, a serious and expanding mental health issue, as a result of their emotional, social, and academic difficulties. This research examines how well a multi-component treatment method might reduce sad symptoms and indicators in high school pupils attending certain Kollam, Kerala, schools. In order to develop a comprehensive and student-centered therapeutic model, the study uses an organized intervention approach that combines cognitive-behavioral therapy, mindfulness-based techniques, interpersonal therapy, and family counselling. Pre-test and post-test evaluations were part of a quantitative, quasi-experimental technique used to evaluate the intervention\'s effectiveness. Both before and after treatment, depression symptoms were measured using standardized psychometric instruments. The results show a significant increase in academic engagement, interpersonal behaviour, cognitive performance, and emotional well-being when comparing the multi-component treatment group to the control group. The findings support the idea that a thorough, school-based psychological intervention might be a practical and expandable method of lowering teenage depression. The research highlights the need of early mental health intervention in educational settings and supports the use of multi-component treatment models in school mental health programs. Suggestions for further research in comparable demographic contexts and policy-level implementation are included.
KEYWORDS : Keywords: multi-component treatment, cognitive-behavioral therapy, High school kids, Kollam, Kerala

Paper Title

FORMULATION AND EVALUATION OF HERBAL FACEPACK

Abstract

The present study focuses on the formulation and evaluation of an herbal face pack using natural plant-based ingredients known for their skin-enhancing, cleansing, and therapeutic properties. The formulation was developed by incorporating herbal powders such as Multani mitti, neem, turmeric, rose, orange peel, and sandalwood, selected for their antimicrobial, anti-inflammatory, antioxidant, and skin-brightening activities. The prepared face pack was evaluated for various physicochemical parameters including organoleptic characteristics, pH, particle size, spreadability, washability, stability, and irritancy. Results indicated that the herbal face pack demonstrated good consistency, acceptable pH compatible with skin, smooth texture, easy washability, and excellent stability under different storage conditions. The product showed no skin irritation and exhibited promising cleansing, oil-absorption, and complexion-improving effects. Overall, the study suggests that herbal face packs can be a safe, effective, and economical alternative to synthetic cosmetic formulations.
KEYWORDS : Herbal cosmetics , Multani mitti , Neem, Turmeric, Rose powder, Orange peel, Stability studies

Paper Title

FORMULATION AND EVALUATION OF NATURAL TOOTH POWDER

Abstract

The arranged Tooth Powder was assessed for its organoleptic and physical characteristics such as color, smell, taste, soundness, foam ability and abrasiveness to guarantee that it have all the specified highlights to utilize against the dental illness. The result was found inside the allowed limits. Dentrifires are the item which is utilized to preserve the Verbal Hygiene such as Freshness of mouth and to maintain a strategic distance from tooth rot. The verbal cleanliness can be kept up all through the day by utilizing different dentrifires arranged by home grown and engineered fixings. This work was carried out to get ready Tooth powder which can be utilized as a instrument for legitimate verbal cleanliness and to overcome the side impact of the ordinary Tooth control arranged by engineered fixings. The Tooth Powder was arranged by utilizing different home grown fixings which have the antibacterial, clean and cooling properties, Unique Powders are pharmaceutical strong measurement shape experienced in nearly each perspective of drug store both in industry and in home. A pharmaceutical powder could be a blend of finely isolated drugs and chemicals in dry shape, which are implied for inner and outside utilize. The display work is aimed to clarify the pertinence of toothpowder within the current situation. The by and large think about concludes around the characteristics, sorts, properties, arrangement and assessment of toothpowder. Herbal tooth powders comprising of different fixings that are accessible within the advertise in a wide run. Subsequently advanced strategies centering on these viewpoints are valuable for the standardization of herbs and their details. Customers accepted by using herbal-based toothpowders are secure, successful, and less harmful. The verbal depression contaminations are the foremost common sorts of diseases. Dental caries is an irresistible infection, causes harm and contamination of finish and dentine. In the event that it isn\'t treated, the infection continues and will lead to tooth misfortune. The mouth contains typical greenery of deft microbes that are ordinarily non-pathogenic. The awkwardness of this circumstance causes disease and tooth rot. Streptococcus mutants are considered as the main species included within the advancement of dental caries. S. mutants, acid-producing microscopic organisms, causes aging of carbohydrates which comes about in tooth decay. In this manner, within the show work, the taking after perspectives of Home grown tooth powders were arranged for the definition, standardization of home grown tooth powder, and anti-bacterial screening of the extricates of herbal tooth powder.
KEYWORDS : Herbal ingredients, oral hygiene, Antibacterial activity. Dental caries. herbal tooth powder

Paper Title

STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF MECLIZINE AND CYCLIZINE ON HPLC

Abstract

Stability-indicating analytical methods play a critical role in pharmaceutical quality assurance by enabling accurate quantification of drug substances in the presence of degradation products. Meclizine and Cyclizine are antihistaminic agents widely prescribed for the management of nausea, vertigo, and motion sickness, and their analytical determination in combined or co-administered formulations is essential for ensuring therapeutic efficacy and product stability. This review provides a comprehensive overview of reported stability-indicating chromatographic and spectrophotometric methods developed for the simultaneous estimation of Meclizine hydrochloride and Cyclizine hydrochloride. The article summarizes analytical advancements in RP-HPLC, HPTLC, UPLC, UV-spectrophotometry, derivative spectrophotometry, and chemometric approaches, focusing on method optimization, chromatographic conditions, detection wavelengths, and separation efficiency. Special emphasis is placed on forced degradation studies under stress conditions such as acid/base hydrolysis, oxidation, photolysis, and thermal exposure, demonstrating the capability of these methods to discriminate active drugs from their degradants in compliance with ICH Q1A(R2) and Q2(R1) guidelines. Challenges associated with co-elution, matrix interference, and simultaneous drug quantification are discussed along with future prospects including green analytical chemistry and hyphenated analytical techniques. This review highlights that validated stability-indicating analytical methods represent an indispensable tool for quality control laboratories and regulatory submissions for pharmaceutical products containing Meclizine and Cyclizine
KEYWORDS : Meclizine, Cyclizine, Stability-indicating method, RP-HPLC, Simultaneous estimation, Forced degradation, ICH guidelines, Analytical validation.

Paper Title

COMPARATIVE PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF DRYNARIA QUERCIFOLIA (L.) J. SM LEAF

Abstract

Drynaria quercifolia (L.) is an important medicinal fern known for its rich phytochemical composition and antioxidant properties. The present study aimed to compare the phytochemical constituents and antioxidant activity of fresh and dried leaves of Drynaria quercifolia (L.) using different solvents. Leaf extracts were prepared using chloroform, acetone, and water to evaluate the effect of leaf condition and solvent polarity on bioactive compounds. Qualitative phytochemical screening revealed the presence of flavonoids, phenolics, tannins, saponins, alkaloids, and terpenoids in both fresh and dried leaf extracts, with noticeable variation in their distribution. Quantitative analysis indicated that dried leaf extracts contained higher levels of total phenolic and flavonoid contents compared to fresh leaves. Antioxidant activity assessed through in vitro free radical scavenging assays showed that dried leaf extracts exhibited greater antioxidant potential than fresh leaf extracts. Among the solvents used, acetone and aqueous extracts demonstrated superior antioxidant activity compared to chloroform extracts. The results suggest that drying enhances phytochemical extraction and antioxidant efficiency, while solvent selection significantly influences the recovery of bioactive compounds. This study confirms the potential of Drynaria quercifolia (L.) leaves as a natural source of antioxidants and supports their therapeutic significance.
KEYWORDS : comparative analysis, Drynaria quercifolia (L.), Antioxidants, Phytochemical constituents, DPPH

Paper Title

SPATIAL DISTRIBUTION PATTERNS OF TROPICAL LAMIACEAE AND THEIR RELATIONSHIP WITH MICROHABITAT VARIABLES

Abstract

The study also evaluates anthropogenic pressures affecting these species and proposes recommendations for their conservation and sustainable utilization. Tropical Lamiaceae species demonstrate remarkable ecological plasticity, allowing them to thrive in diverse environmental conditions ranging from humid rainforests and tropical deciduous forests to scrublands and montane ecosystems. These species contribute substantially to ecological stability, biodiversity conservation, ethnobotanical value, and pharmaceutical research. The present study investigates the ecological characteristics, adaptive strategies, habitat associations, and functional roles of tropical Lamiaceae species, with a focus on understanding their distribution patterns, environ-mental preferences, and interactions within tropical landscapes. Their characteristic morphological traits—square stems, glandular trichomes, and aromatic essential oils—not only help in reducing herbivory and water loss but also contribute to species interactions with pollinators and other organisms. Many genera such as Ocimum, Pogostemon, Leucas, Coleus, Vitex, and Hyptis exhibit strong associations with insect pollinators, especially bees and butterflies, thereby playing an essential role in maintaining pollination networks in tropical regions.
KEYWORDS : Tropical Lamiaceae, tropical landscapes, ecological plasticity, glandular trichomes, Pogostemon, tropical regions.

Paper Title

A STUDY TO ASSESS THE EFFECTIVENESS OF THE SELF- INSTRUCTIONAL MODULE REGARDING PHOTOTHERAPY IN TERMS OF KNOWLEDGE AND PRACTICE AMONG STAFF NURSES WORKING IN NICU AT SELECTED HOSPITALS IN VIJAYAPURA, KARNATAKA

Abstract

Phototherapy is a critical and widely used intervention in management of neonatal hyperbilirubinemia in Neonatal Intensive Care Units (NICUs). Effective administration of phototherapy requires adequate knowledge & competent practice among staff nurses to ensure neonatal safety and optimal therapeutic outcomes. Present study aimed to assess the effectiveness of a Self-Instructional Module (SIM) regarding phototherapy in terms of knowledge and practice among staff nurses working in NICUs at selected hospitals in Vijayapura, Karnataka. A quantitative research approach with a pre-experimental one-group pretest–post-est design was adopted. Self-Instructional Module was administered after the pretest, followed by a post-test to evaluate its effectiveness. The findings revealed a significant improvement in both knowledge and practice scores of staff nurses after the implementation of the SIM indicating its effectiveness as an educational strategy.
KEYWORDS : Phototherapy, Self-Instructional Module, Knowledge, Practice & Staff Nurses