Paper Title
DETECTION AND MANAGEMENT OF ADRS IN TERTIARY HOSPITAL IN INDIAAbstract
Adverse drug reactions (ADRs) are a major cause of morbidity and hospitalizations have consistently increased, leading to economic burden to developing countries like India. Identification of ADRs and their reporting pattern can provide useful information for their management. Medicines that treat illnesses can modify, mostly in a beneficial manner, the physiological processes in the body. At the same time, drugs always carry a certain amount of risk, in the form of unintended or unwanted side effects, also known as Adverse Drug Reactions (ADRs). The utility of a medicine depends on a combination of the extent of expected benefits of the remedy and the seriousness of possible unwanted effects. Every time a community is exposed to a new medication, the risk of ADRs increases. This occurs when a new drug is introduced into the market for the first time. No drug is absolutely safe, even when prescribed in therapeutic doses. The World Health Organization (WHO) defines Pharmacovigilance (PV) as “the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects of drugs. An ADR is a reaction to a drug and/or a combination of drugs which is harmful and unintended and which occurs at a dose that is normally used for prophylaxis, diagnosis or treatment. This study is mainly focus on Detection and management of ADRs in Tertiary Hospital. It is suggested that the most appropriate approach of medication control to minimize the incidence of ADR is screening the total medication of the individual patient by a hospital/clinical pharmacist and by taking history of allergy as well as past medication and medical history.
KEYWORDS : Adverse drug reaction, medicines, physiological process, WHO, pharmacovigilance, tertiary hospital